The misadventures of Karan (Tusshar Kapoor) and Sakshi (Aftab Shivdasani), two incredibly dim-witted but optimistic friends who dream of becoming famous actors in the Mumbai film industry. They share a cramped apartment with their more sensible friend, Rocket (Krishna Abhishek).
Their big break seems to arrive when they are hired as background dancers for a famous Bollywood item number. However, their lives take an absurd turn when they accidentally interrupt a black magic ritual performed by a tantrik baba. During the ensuing chaos, a lightning bolt strikes, causing their souls to be transferred out of their bodies.
The Soul Swap: Karan and Sakshi's souls don't just disappear; they end up swapping into the bodies of two women: a homely, bespectacled woman named Radhika and a bold, fashion-forward woman named Monica.
Navigating New Lives: The majority of the film's comedy stems from the two men (now in female bodies) trying to cope with their new reality. This includes dealing with periods, wearing women's clothing, avoiding unwanted male attention, and trying to explain their situation to a bewildered Rocket.
The Quest for Reversal: Their primary goal becomes finding the tantrik baba to reverse the soul swap. Their quest leads them through a series of raunchy, slapstick, and often crass comedic set-pieces.
The Resolution: The plot, which is largely a framework for adult jokes, culminates in them finally tracking down the baba and attempting to reverse the spell, leading to more chaotic and suggestive situations.